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Fusion cytokine IL-2-GMCSF enhances anticancer immune responses through promoting cell–cell interactions

BACKGROUND: Potent antitumor responses can be induced through cytokine immunotherapy. Interleukin (IL)-2 and granulocyte–macrophage colony-stimulating factor (GM-CSF) are among the most effective cytokines to induce tumor-specific systemic immune responses and can act synergistically. To overcome th...

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Detalles Bibliográficos
Autores principales: Wen, Qian, Xiong, Wenjing, He, Jianchun, Zhang, Shimeng, Du, Xialin, Liu, Sudong, Wang, Juanjuan, Zhou, Mingqian, Ma, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743407/
https://www.ncbi.nlm.nih.gov/pubmed/26850448
http://dx.doi.org/10.1186/s12967-016-0799-7