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Fusion cytokine IL-2-GMCSF enhances anticancer immune responses through promoting cell–cell interactions
BACKGROUND: Potent antitumor responses can be induced through cytokine immunotherapy. Interleukin (IL)-2 and granulocyte–macrophage colony-stimulating factor (GM-CSF) are among the most effective cytokines to induce tumor-specific systemic immune responses and can act synergistically. To overcome th...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743407/ https://www.ncbi.nlm.nih.gov/pubmed/26850448 http://dx.doi.org/10.1186/s12967-016-0799-7 |