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Marked seasonality of Cyclospora cayetanensis infections: ten-year observation of hospital cases, Honduras

BACKGROUND: Document seasonality occurrence and epidemiologic characteristics of Cyclospora cayetanensis infections during a 10-year period from patients consulting at the University Hospital, Honduras. METHODS: Retrospective non interventional hospital-based study analyzed laboratory results from t...

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Autores principales: Kaminsky, Rina Girard, Lagos, Javier, Raudales Santos, Gabriela, Urrutia, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743408/
https://www.ncbi.nlm.nih.gov/pubmed/26847438
http://dx.doi.org/10.1186/s12879-016-1393-6
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author Kaminsky, Rina Girard
Lagos, Javier
Raudales Santos, Gabriela
Urrutia, Samuel
author_facet Kaminsky, Rina Girard
Lagos, Javier
Raudales Santos, Gabriela
Urrutia, Samuel
author_sort Kaminsky, Rina Girard
collection PubMed
description BACKGROUND: Document seasonality occurrence and epidemiologic characteristics of Cyclospora cayetanensis infections during a 10-year period from patients consulting at the University Hospital, Honduras. METHODS: Retrospective non interventional hospital-based study analyzed laboratory results from the period 2002 to 2011 of fresh and Ziehl-Nielsen carbolfuchsin stained routine stool samples received for parasitologic examination. Sporadically a sample with numerous oocysts was allowed to sporulate in 2.5 % potassium dichromate confirming the presence of bi-cystic bi-zoic oocysts. RESULTS: A total of 35,157 fecal samples were examined during a ten-year span, of which a third (28.4 %) was stained by the Ziehl-Neelsen carbolfuchsin method diagnosing a total of 125 (1.3 %) C.cayetanensis infections. A statistically significant apparent seasonality was observed most years during May to August (range p < 0.036–0.001), with 83.3 % of 125 cases occurring in those rainy months. All C. cayetanensis cases came from urban poor neighborhoods; male/female relation was 1:1 except in 2006, when all patients were females (p = 0.05; r(2) = 22,448). Forty four point eight percent of the stool samples were diarrheic or liquid and 65.6 % infections were identified in children 10 years old or less. Enteric helminths and protozoa co-infected Cyclospora positive patients in 52 instances.: 8 % Ascaris lumbricoides, 8 % Giardia duodenalis, 23.2 % Blastocystis spp. and less frequently Entamoeba histolytica/E. dispar, Strongyloides stercoralis, and Trichuris trichiura. CONCLUSIONS: Results suggest a seasonal pattern for Cyclospora infections diagnosed in a clinical setting during the rainy months in Tegucigalpa and surrounding areas. Community studies should be conducted to support or dispute these observations.
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spelling pubmed-47434082016-02-06 Marked seasonality of Cyclospora cayetanensis infections: ten-year observation of hospital cases, Honduras Kaminsky, Rina Girard Lagos, Javier Raudales Santos, Gabriela Urrutia, Samuel BMC Infect Dis Research Article BACKGROUND: Document seasonality occurrence and epidemiologic characteristics of Cyclospora cayetanensis infections during a 10-year period from patients consulting at the University Hospital, Honduras. METHODS: Retrospective non interventional hospital-based study analyzed laboratory results from the period 2002 to 2011 of fresh and Ziehl-Nielsen carbolfuchsin stained routine stool samples received for parasitologic examination. Sporadically a sample with numerous oocysts was allowed to sporulate in 2.5 % potassium dichromate confirming the presence of bi-cystic bi-zoic oocysts. RESULTS: A total of 35,157 fecal samples were examined during a ten-year span, of which a third (28.4 %) was stained by the Ziehl-Neelsen carbolfuchsin method diagnosing a total of 125 (1.3 %) C.cayetanensis infections. A statistically significant apparent seasonality was observed most years during May to August (range p < 0.036–0.001), with 83.3 % of 125 cases occurring in those rainy months. All C. cayetanensis cases came from urban poor neighborhoods; male/female relation was 1:1 except in 2006, when all patients were females (p = 0.05; r(2) = 22,448). Forty four point eight percent of the stool samples were diarrheic or liquid and 65.6 % infections were identified in children 10 years old or less. Enteric helminths and protozoa co-infected Cyclospora positive patients in 52 instances.: 8 % Ascaris lumbricoides, 8 % Giardia duodenalis, 23.2 % Blastocystis spp. and less frequently Entamoeba histolytica/E. dispar, Strongyloides stercoralis, and Trichuris trichiura. CONCLUSIONS: Results suggest a seasonal pattern for Cyclospora infections diagnosed in a clinical setting during the rainy months in Tegucigalpa and surrounding areas. Community studies should be conducted to support or dispute these observations. BioMed Central 2016-02-04 /pmc/articles/PMC4743408/ /pubmed/26847438 http://dx.doi.org/10.1186/s12879-016-1393-6 Text en © Kaminsky et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Kaminsky, Rina Girard
Lagos, Javier
Raudales Santos, Gabriela
Urrutia, Samuel
Marked seasonality of Cyclospora cayetanensis infections: ten-year observation of hospital cases, Honduras
title Marked seasonality of Cyclospora cayetanensis infections: ten-year observation of hospital cases, Honduras
title_full Marked seasonality of Cyclospora cayetanensis infections: ten-year observation of hospital cases, Honduras
title_fullStr Marked seasonality of Cyclospora cayetanensis infections: ten-year observation of hospital cases, Honduras
title_full_unstemmed Marked seasonality of Cyclospora cayetanensis infections: ten-year observation of hospital cases, Honduras
title_short Marked seasonality of Cyclospora cayetanensis infections: ten-year observation of hospital cases, Honduras
title_sort marked seasonality of cyclospora cayetanensis infections: ten-year observation of hospital cases, honduras
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743408/
https://www.ncbi.nlm.nih.gov/pubmed/26847438
http://dx.doi.org/10.1186/s12879-016-1393-6
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