Emergence of two prion subtypes in ovine PrP transgenic mice infected with human MM2-cortical Creutzfeldt-Jakob disease prions

INTRODUCTION: Mammalian prions are proteinaceous pathogens responsible for a broad range of fatal neurodegenerative diseases in humans and animals. These diseases can occur spontaneously, such as Creutzfeldt-Jakob disease (CJD) in humans, or be acquired or inherited. Prions are primarily formed of m...

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Detalles Bibliográficos
Autores principales: Chapuis, Jérôme, Moudjou, Mohammed, Reine, Fabienne, Herzog, Laetitia, Jaumain, Emilie, Chapuis, Céline, Quadrio, Isabelle, Boulliat, Jacques, Perret-Liaudet, Armand, Dron, Michel, Laude, Hubert, Rezaei, Human, Béringue, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743415/
https://www.ncbi.nlm.nih.gov/pubmed/26847207
http://dx.doi.org/10.1186/s40478-016-0284-9

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