Cargando…

A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma

Means to cause an immunogenic cell death could lead to significant insight into how cancer escapes immune control. In this study, we screened a library of five pyrrole–imidazole polyamides coding for different DNA sequences in a model of B-cell lymphoma for the upregulation of surface calreticulin,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, JeenJoo S., Dervan, Peter B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743504/ https://www.ncbi.nlm.nih.gov/pubmed/26537405 http://dx.doi.org/10.1017/S0033583515000104

Ejemplares similares

Design of Sequence-Specific DNA Binding Molecules for DNA Methyltransferase Inhibition
por: Kang, JeenJoo S., et al.
Publicado: (2014)

Small Molecule Drugs That Inhibit Phagocytosis
por: Loriamini, Melika, et al.
Publicado: (2023)

Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis
por: Miles, Luke A., et al.
Publicado: (2019)

Guiding the Design of Synthetic DNA-Binding Molecules with Massively Parallel Sequencing
por: Meier, Jordan L., et al.
Publicado: (2012)

Chimeric antigen receptors that trigger phagocytosis
por: Morrissey, Meghan A, et al.
Publicado: (2018)

DNA microstructure influences selective binding of small molecules designed to target mixed-site DNA sequences
por: Laughlin-Toth, Sarah, et al.
Publicado: (2017)

Inhibition of Respiration of Candida albicans by Small Molecules Increases Phagocytosis Efficacy by Macrophages
por: Cui, Shuna, et al.
Publicado: (2020)

Caffeine-induced release of small molecules from DNA nanostructures
por: Madhanagopal, Bharath Raj, et al.
Publicado: (2023)

Genome Replication Is Associated With Release of Immunogenic DNA Waste
por: Schubert, Nadja, et al.
Publicado: (2022)

Estrogen binding by leukocytes during phagocytosis,
Publicado: (1977)

Highly Parallel Translation of DNA Sequences into Small Molecules
por: Weisinger, Rebecca M., et al.
Publicado: (2012)

Dying of Stress: Chemotherapy, Radiotherapy, and Small-Molecule Inhibitors in Immunogenic Cell Death and Immunogenic Modulation
por: Fabian, Kellsye P., et al.
Publicado: (2022)

Deep Sequencing of MYC DNA-Binding Sites in Burkitt Lymphoma
por: Seitz, Volkhard, et al.
Publicado: (2011)

An Exploration of Small Molecules That Bind Human Single-Stranded DNA Binding Protein 1
por: Schuurs, Zachariah P., et al.
Publicado: (2023)

STAT1:DNA sequence-dependent binding modulation by phosphorylation, protein:protein interactions and small-molecule inhibition
por: Bonham, Andrew J., et al.
Publicado: (2013)

The Benzothiazine Core as a Novel Motif for DNA-Binding Small Molecules
por: Mlakić, Milena, et al.
Publicado: (2023)

Phosphatidylserine externalization, “necroptotic bodies” release, and phagocytosis during necroptosis
por: Zargarian, Sefi, et al.
Publicado: (2017)

Evaluating Molecular Docking Software for Small Molecule Binding to G-Quadruplex DNA
por: Dickerhoff, Jonathan, et al.
Publicado: (2021)

Recognition of small molecule–RNA binding sites using RNA sequence and structure
por: Su, Hong, et al.
Publicado: (2021)

Method for Identifying Sequence Motifs in Pre-miRNAs for Small-Molecule Binding
por: Takashima, Yusuke, et al.
Publicado: (2022)

Induced topological changes in DNA complexes: influence of DNA sequences and small molecule structures
por: Hunt, Rebecca A., et al.
Publicado: (2011)

Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding
por: Agyeman, Akwasi, et al.
Publicado: (2014)

A Small Vimentin-Binding Molecule Blocks Cancer Exosome Release and Reduces Cancer Cell Mobility
por: Wu, Jianping, et al.
Publicado: (2021)

Light-Triggered Sequence-Specific Cargo Release from DNA Block Copolymer-Lipid Vesicles**
por: Rodríguez-Pulido, Alberto, et al.
Publicado: (2013)

Characterization of Binding and Phagocytosis of Oxidatively Damaged Erythrocyte to Macrophage
por: Ko, Hong Sook, et al.
Publicado: (2002)

A smart polymer for sequence-selective binding, pulldown, and release of DNA targets
por: Krieg, Elisha, et al.
Publicado: (2020)

DNA–Liposome Hybrid Carriers for Triggered Cargo Release
por: Baumann, Kevin N., et al.
Publicado: (2022)

Small Molecule‐Templated DNA Hydrogel with Record Stiffness Integrates and Releases DNA Nanostructures and Gene Silencing Nucleic Acids
por: Lachance‐Brais, Christophe, et al.
Publicado: (2023)

Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry
por: Litovchick, Alexander, et al.
Publicado: (2019)

Slipped-CAG DNA binding small molecule induces trinucleotide repeat contractions in vivo
por: Nakamori, Masayuki, et al.
Publicado: (2020)

Label-free profiling of DNA aptamer-small molecule binding using T5 exonuclease
por: Alkhamis, Obtin, et al.
Publicado: (2020)

Sequence specific suppression of androgen receptor–DNA binding in vivo by a Py-Im polyamide
por: Kurmis, Alexis A, et al.
Publicado: (2019)

Protein coated microcrystals formulated with model antigens and modified with calcium phosphate exhibit enhanced phagocytosis and immunogenicity()
por: Jones, Sarah, et al.
Publicado: (2014)

Cryptococcus neoformans Is Internalized by Receptor-Mediated or ‘Triggered’ Phagocytosis, Dependent on Actin Recruitment
por: Guerra, Caroline Rezende, et al.
Publicado: (2014)

Serum from half of patients with immune thrombocytopenia trigger macrophage phagocytosis of platelets
por: Norris, Peter A. A., et al.
Publicado: (2023)

Small molecule-induced polymerization triggers degradation of BCL6
por: Słabicki, Mikołaj, et al.
Publicado: (2020)

TTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets
por: Lin, Gloria H. Y., et al.
Publicado: (2017)

Phagocytosis
Publicado: (1892)

On Phagocytosis
Publicado: (1907)

Pathogen-Specific Binding Soluble Down Syndrome Cell Adhesion Molecule (Dscam) Regulates Phagocytosis via Membrane-Bound Dscam in Crab
por: Li, Xue-Jie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4t29nb448a6td6bcghge95tbjm