Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile

Antibiotic resistance is a global health concern meaning there is an urgent need for new treatments and diagnostics. Here glycosylated surfaces are used to profile the binding patterns of a range of Gram-negative, Gram-positive and mycobacteria. This enables the creation of ‘barcodes’ to enable iden...

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Detalles Bibliográficos
Autores principales: Otten, Lucienne, Fullam, Elizabeth, Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743676/
https://www.ncbi.nlm.nih.gov/pubmed/26647648
http://dx.doi.org/10.1039/c5mb00720h
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author Otten, Lucienne
Fullam, Elizabeth
Gibson, Matthew I.
author_facet Otten, Lucienne
Fullam, Elizabeth
Gibson, Matthew I.
author_sort Otten, Lucienne
collection PubMed
description Antibiotic resistance is a global health concern meaning there is an urgent need for new treatments and diagnostics. Here glycosylated surfaces are used to profile the binding patterns of a range of Gram-negative, Gram-positive and mycobacteria. This enables the creation of ‘barcodes’ to enable identification and discrimination between the strains, which could not be achieved by single-point glycan binding and offers a new concept in bacteria detection.
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spelling pubmed-47436762016-02-22 Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile Otten, Lucienne Fullam, Elizabeth Gibson, Matthew I. Mol Biosyst Chemistry Antibiotic resistance is a global health concern meaning there is an urgent need for new treatments and diagnostics. Here glycosylated surfaces are used to profile the binding patterns of a range of Gram-negative, Gram-positive and mycobacteria. This enables the creation of ‘barcodes’ to enable identification and discrimination between the strains, which could not be achieved by single-point glycan binding and offers a new concept in bacteria detection. Royal Society of Chemistry 2016-02-26 2015-12-09 /pmc/articles/PMC4743676/ /pubmed/26647648 http://dx.doi.org/10.1039/c5mb00720h Text en This journal is © The Royal Society of Chemistry 2015 http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Otten, Lucienne
Fullam, Elizabeth
Gibson, Matthew I.
Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile
title Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile
title_full Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile
title_fullStr Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile
title_full_unstemmed Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile
title_short Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile
title_sort discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743676/
https://www.ncbi.nlm.nih.gov/pubmed/26647648
http://dx.doi.org/10.1039/c5mb00720h
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