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Constitutively Active MAVS Inhibits HIV-1 Replication via Type I Interferon Secretion and Induction of HIV-1 Restriction Factors

Type I interferon is known to inhibit HIV-1 replication through the induction of interferon stimulated genes (ISG), including a number of HIV-1 restriction factors. To better understand interferon-mediated HIV-1 restriction, we constructed a constitutively active form of the RIG-I adapter protein MA...

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Detalles Bibliográficos
Autores principales:	Gupta, Sachin, Termini, James M., Issac, Biju, Guirado, Elizabeth, Stone, Geoffrey W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743994/ https://www.ncbi.nlm.nih.gov/pubmed/26849062 http://dx.doi.org/10.1371/journal.pone.0148929

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