Cargando…

Establishment of Leptin-Responsive Cell Lines from Adult Mouse Hypothalamus

Leptin resistance is considered to be the primary cause of obesity. However, the cause of leptin resistance remains incompletely understood, and there is currently no cure for the leptin-resistant state. In order to identify novel drug-target molecules that could overcome leptin resistance, it would...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iwakura, Hiroshi, Dote, Katsuko, Bando, Mika, Koyama, Hiroyuki, Hosoda, Kiminori, Kangawa, Kenji, Nakao, Kazuwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744015/ https://www.ncbi.nlm.nih.gov/pubmed/26849804 http://dx.doi.org/10.1371/journal.pone.0148639

Ejemplares similares

Effectiveness of nationwide screening and lifestyle intervention for abdominal obesity and cardiometabolic risks in Japan: The metabolic syndrome and comprehensive lifestyle intervention study on nationwide database in Japan (MetS ACTION-J study)
por: Nakao, Yoko M., et al.
Publicado: (2018)

Therapeutic Impact of Leptin on Diabetes, Diabetic Complications, and Longevity in Insulin-Deficient Diabetic Mice
por: Naito, Masaki, et al.
Publicado: (2011)

Implication of C-type natriuretic peptide derived from vascular endothelial cells on blood pressure regulation
por: Nakao, Kazuwa, et al.
Publicado: (2015)

The G-Protein-Coupled Long-Chain Fatty Acid Receptor GPR40 and Glucose Metabolism
por: Tomita, Tsutomu, et al.
Publicado: (2014)

C-type natriuretic peptide is a Schwann cell-derived factor for development and function of sensory neurons
por: Kishimoto, Ichiro, et al.
Publicado: (2009)

Translational science: Newly emerging science in biology and medicine — Lessons from translational research on the natriuretic peptide family and leptin —
por: NAKAO, Kazuwa
Publicado: (2019)

Ghrelin and Functional Dyspepsia
por: Akamizu, Takashi, et al.
Publicado: (2010)

Leptin potentiates astrogenesis in the developing hypothalamus
por: Rottkamp, Daniele M., et al.
Publicado: (2015)

Endothelial GC-A can be a therapeutic target for metabolic syndrome
por: Tokudome, Takeshi, et al.
Publicado: (2013)

Intra-abdominal fat area is a predictor for new onset of individual components of metabolic syndrome: MEtabolic syndRome and abdominaL ObesiTy (MERLOT study)
por: NAKAO, Yoko M., et al.
Publicado: (2012)

Natriuretic Peptide Signaling via Guanylyl Cyclase (GC)-A: An Endogenous Protective Mechanism of the Heart
por: Kishimoto, Ichiro, et al.
Publicado: (2009)

Analysis of mitochondrial function in human induced pluripotent stem cells from patients with mitochondrial diabetes due to the A3243G mutation
por: Matsubara, Masaki, et al.
Publicado: (2018)

Adipocyte-specific expression of C-type natriuretic peptide suppresses lipid metabolism and adipocyte hypertrophy in adipose tissues in mice fed high-fat diet
por: Bae, Cho-Rong, et al.
Publicado: (2018)

Protective role of endogenous cardiac natriuretic peptide/GC-A system on the maternal heart during the postpartum period
por: Otani, Kentaro, et al.
Publicado: (2013)

Living without insulin: the role of leptin signaling in the hypothalamus
por: Fujikawa, Teppei, et al.
Publicado: (2015)

PTPRJ Inhibits Leptin Signaling, and Induction of PTPRJ in the Hypothalamus Is a Cause of the Development of Leptin Resistance
por: Shintani, Takafumi, et al.
Publicado: (2017)

Effect of Acupoint Embedding on Serum Leptin and Hypothalamus Leptin Receptor Expression in Rats with Simple Obesity
por: Yang, Qiming, et al.
Publicado: (2021)

Angiopoietin-Like Growth Factor Involved in Leptin Signaling in the Hypothalamus
por: Jang, Yunseon, et al.
Publicado: (2021)

ANP/GC-A signaling attenuates tissue injury by cisplatin
por: Nojiri, Takashi, et al.
Publicado: (2013)

Optogenetic activation of leptin- and glucose-regulated GABAergic neurons in dorsomedial hypothalamus promotes food intake via inhibitory synaptic transmission to paraventricular nucleus of hypothalamus
por: Otgon-Uul, Zesemdorj, et al.
Publicado: (2016)

Sexual maturation in hens is not associated with increases in serum leptin and the expression of leptin receptor mRNA in hypothalamus
por: Ni, Yingdong, et al.
Publicado: (2013)

Ciliary Neurotrophic Factor Acts on Distinctive Hypothalamic Arcuate Neurons and Promotes Leptin Entry Into and Action on the Mouse Hypothalamus
por: Venema, Wiebe, et al.
Publicado: (2020)

Endurance exercise is a leptin signaling mimetic in hypothalamus of Wistar rats
por: Zhao, Jiexiu, et al.
Publicado: (2011)

Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus
por: Biddinger, Jessica E, et al.
Publicado: (2020)

Leptin receptor neurons in the dorsomedial hypothalamus input to the circadian feeding network
por: Tang, Qijun, et al.
Publicado: (2023)

A novel physiological significance of natriuretic peptides in cancer metastasis
por: Kangawa, Kenji, et al.
Publicado: (2013)

ANP/GC-A signaling attenuates pulmonary metastasis of B16 melanoma enhanced by lipopolysaccharide or angiotensin-II
por: Nojiri, Takashi, et al.
Publicado: (2013)

CNP attenuates renal toxicity induced by cisplatin in murine kidney
por: Kimura, Toru, et al.
Publicado: (2015)

Overexpression of C-type Natriuretic Peptide in Endothelial Cells Protects against Insulin Resistance and Inflammation during Diet-induced Obesity
por: Bae, Cho-Rong, et al.
Publicado: (2017)

Intracerebroventricular Administration of C-Type Natriuretic Peptide Suppresses Food Intake via Activation of the Melanocortin System in Mice
por: Yamada-Goto, Nobuko, et al.
Publicado: (2013)

Different distribution of neuromedin S and its mRNA in the rat brain: NMS peptide is present not only in the hypothalamus as the mRNA, but also in the brainstem
por: Mori, Miwa, et al.
Publicado: (2012)

Neuropeptide Y and leptin receptor expression in the hypothalamus of rats with chronic immobilization stress
por: Wang, Shaoxian, et al.
Publicado: (2013)

Antagonistic interplay between hypocretin and leptin in the lateral hypothalamus regulates stress responses
por: Bonnavion, Patricia, et al.
Publicado: (2015)

Possible Integrative Actions of Leptin and Insulin Signaling in the Hypothalamus Targeting Energy Homeostasis
por: Thon, Mina, et al.
Publicado: (2016)

Molecular profile and response to energy deficit of leptin-receptor neurons in the lateral hypothalamus
por: Kakava-Georgiadou, N., et al.
Publicado: (2022)

The effects of super-flux (high performance) dialyzer on the plasma glycosylated pro-B-type natriuretic peptide (proBNP) and glycosylated N-terminal proBNP in end-stage renal disease patients on dialysis
por: Nakagawa, Yasuaki, et al.
Publicado: (2013)

Newly established cell lines from mouse oral epithelium regenerate teeth when combined with dental mesenchyme
por: Takahashi, Chiho, et al.
Publicado: (2009)

The world's first clinical randomized trial of atrial natriuretic peptide for preventing cancer recurrence following lung cancer surgery
por: Nojiri, Takashi, et al.
Publicado: (2015)

Effects of Reduced Weight Maintenance and Leptin Repletion on Functional Connectivity of the Hypothalamus in Obese Humans
por: Hinkle, William, et al.
Publicado: (2013)

Effects of GABA and Leptin Receptor‐Expressing Neurons in the Lateral Hypothalamus on Feeding, Locomotion, and Thermogenesis
por: de Vrind, Véronne A.J., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_738k7oavsa7c2tuhbmbl0coo2j