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Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein

Influenza A viruses (IAVs) inhibit host gene expression by a process known as host shutoff. Host shutoff limits host innate immune responses and may also redirect the translation apparatus to the production of viral proteins. Multiple IAV proteins regulate host shutoff, including PA-X, a ribonucleas...

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Detalles Bibliográficos
Autores principales:	Khaperskyy, Denys A., Schmaling, Summer, Larkins-Ford, Jonah, McCormick, Craig, Gaglia, Marta M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744033/ https://www.ncbi.nlm.nih.gov/pubmed/26849127 http://dx.doi.org/10.1371/journal.ppat.1005427

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