The Position of His-Tag in Recombinant OspC and Application of Various Adjuvants Affects the Intensity and Quality of Specific Antibody Response after Immunization of Experimental Mice

Lyme disease, Borrelia burgdorferi-caused infection, if not recognized and appropriately treated by antibiotics, may lead to chronic complications, thus stressing the need for protective vaccine development. The immune protection is mediated by phagocytic cells and by Borrelia-specific complement-ac...

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Detalles Bibliográficos
Autores principales: Krupka, Michal, Masek, Josef, Barkocziova, Lucia, Turanek Knotigova, Pavlina, Kulich, Pavel, Plockova, Jana, Lukac, Robert, Bartheldyova, Eliska, Koudelka, Stepan, Chaloupkova, Radka, Sebela, Marek, Zyka, Daniel, Droz, Ladislav, Effenberg, Roman, Ledvina, Miroslav, Miller, Andrew D., Turanek, Jaroslav, Raska, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744052/
https://www.ncbi.nlm.nih.gov/pubmed/26848589
http://dx.doi.org/10.1371/journal.pone.0148497

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