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Missense Mutations Allow a Sequence-Blind Mutant of SpoIIIE to Successfully Translocate Chromosomes during Sporulation

SpoIIIE directionally pumps DNA across membranes during Bacillus subtilis sporulation and vegetative growth. The sequence-reading domain (γ domain) is required for directional DNA transport, and its deletion severely impairs sporulation. We selected suppressors of the spoIIIEΔγ sporulation defect. U...

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Detalles Bibliográficos
Autores principales: Bose, Baundauna, Reed, Sydney E., Besprozvannaya, Marina, Burton, Briana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744071/
https://www.ncbi.nlm.nih.gov/pubmed/26849443
http://dx.doi.org/10.1371/journal.pone.0148365

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