Automated Ex Situ Assays of Amyloid Formation on a Microfluidic Platform

Increasingly prevalent neurodegenerative diseases are associated with the formation of nanoscale amyloid aggregates from normally soluble peptides and proteins. A widely used strategy for following the aggregation process and defining its kinetics involves the use of extrinsic dyes that undergo a sp...

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Detalles Bibliográficos
Autores principales: Saar, Kadi-Liis, Yates, Emma V., Müller, Thomas, Saunier, Séverine, Dobson, Christopher M., Knowles, Tuomas P.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2016
Materias:
Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744157/
https://www.ncbi.nlm.nih.gov/pubmed/26840721
http://dx.doi.org/10.1016/j.bpj.2015.11.3523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744157/
https://www.ncbi.nlm.nih.gov/pubmed/26840721
http://dx.doi.org/10.1016/j.bpj.2015.11.3523

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