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Automated Ex Situ Assays of Amyloid Formation on a Microfluidic Platform
Increasingly prevalent neurodegenerative diseases are associated with the formation of nanoscale amyloid aggregates from normally soluble peptides and proteins. A widely used strategy for following the aggregation process and defining its kinetics involves the use of extrinsic dyes that undergo a sp...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744157/ https://www.ncbi.nlm.nih.gov/pubmed/26840721 http://dx.doi.org/10.1016/j.bpj.2015.11.3523 |