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Modeling the Overproduction of Ribosomes when Antibacterial Drugs Act on Cells

Bacteria that are subjected to ribosome-inhibiting antibiotic drugs show an interesting behavior: Although the drug slows down cell growth, it also paradoxically increases the cell’s concentration of ribosomes. We combine our earlier nonlinear model of the energy-biomass balance in undrugged Escheri...

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Detalles Bibliográficos
Autores principales: Maitra, Arijit, Dill, Ken A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744161/
https://www.ncbi.nlm.nih.gov/pubmed/26840738
http://dx.doi.org/10.1016/j.bpj.2015.12.016

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