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Controlled Release from Zein Matrices: Interplay of Drug Hydrophobicity and pH
PURPOSE: In earlier studies, the corn protein zein is found to be suitable as a sustained release agent, yet the range of drugs for which zein has been studied remains small. Here, zein is used as a sole excipient for drugs differing in hydrophobicity and isoelectric point: indomethacin, paracetamol...
Autores principales: | Bouman, Jacob, Belton, Peter, Venema, Paul, van der Linden, Erik, de Vries, Renko, Qi, Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744255/ https://www.ncbi.nlm.nih.gov/pubmed/26582357 http://dx.doi.org/10.1007/s11095-015-1818-8 |
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