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Pharmacokinetics, Tissue Distribution and Therapeutic Effect of Cationic Thermosensitive Liposomal Doxorubicin Upon Mild Hyperthermia
PURPOSE: To evaluate pharmacokinetic profile, biodistribution and therapeutic effect of cationic thermosensitive liposomes (CTSL) encapsulating doxorubicin (Dox) upon mild hyperthermia (HT). METHODS: Non-targeted thermosensitive liposomes (TSL) and CTSL were developed, loaded with Dox and characteri...
Autores principales: | Dicheva, Bilyana M., Seynhaeve, Ann L. B., Soulie, Thomas, Eggermont, Alexander M. M., ten Hagen, Timo L. M., Koning, Gerben A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744262/ https://www.ncbi.nlm.nih.gov/pubmed/26518763 http://dx.doi.org/10.1007/s11095-015-1815-y |
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