Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency

BACKGROUND: While antiretroviral therapies have improved life expectancy and reduced viral loads in HIV-1-positive individuals, the cessation of treatment results in a rebound of viral replication. This suggests that a reservoir of latently-infected cells remains within these patients, the identity...

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Detalles Bibliográficos
Autores principales: Hurst, Tara, Pace, Matthew, Katzourakis, Aris, Phillips, Rodney, Klenerman, Paul, Frater, John, Magiorkinis, Gkikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744380/
https://www.ncbi.nlm.nih.gov/pubmed/26852322
http://dx.doi.org/10.1186/s12977-016-0242-4

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