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Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer

BACKGROUND: Drug resistance in breast cancer is the major obstacle to effective treatment with chemotherapy. While upregulation of multidrug resistance genes is an important component of drug resistance mechanisms in vitro, their clinical relevance remains to be determined. Therefore, identifying pa...

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Detalles Bibliográficos
Autores principales:	Braunstein, Marsela, Liao, Linda, Lyttle, Nicola, Lobo, Nazleen, Taylor, Karen J., Krzyzanowski, Paul M., Kalatskaya, Irina, Yao, Cindy Q., Stein, Lincoln D., Boutros, Paul C., Twelves, Christopher J., Marcellus, Richard, Bartlett, John M. S., Spears, Melanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744406/ https://www.ncbi.nlm.nih.gov/pubmed/26852132 http://dx.doi.org/10.1186/s13058-016-0676-6

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