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Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer

BACKGROUND: Germline mutations in the BRCA1 and BRCA2 genes greatly increase a woman’s risk of developing breast and/or ovarian cancer. The prevalence and distribution of such mutations differ across races/ethnicities. Several studies have investigated Chinese women with high-risk breast cancer, but...

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Detalles Bibliográficos
Autores principales:	Cao, Wen-Ming, Gao, Yun, Yang, Hong-Jian, Xie, Shang-Nao, Ding, Xiao-Wen, Pan, Zhi-Wen, Ye, Wei-Wu, Wang, Xiao-Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744435/ https://www.ncbi.nlm.nih.gov/pubmed/26852015 http://dx.doi.org/10.1186/s12885-016-2107-6

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