P(i) Release Limits the Intrinsic and RNA-Stimulated ATPase Cycles of DEAD-Box Protein 5 (Dbp5)

mRNA export from the nucleus depends on the ATPase activity of the DEAD-box protein Dbp5/DDX19. Although Dbp5 has measurable ATPase activity alone, several regulatory factors (e.g., RNA, nucleoporin proteins, and the endogenous small molecule InsP(6)) modulate catalytic activity in vitro and in vivo...

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Detalles Bibliográficos
Autores principales: Wong, Emily V., Cao, Wenxiang, Vörös, Judit, Merchant, Monique, Modis, Yorgo, Hackney, David D., Montpetit, Ben, De La Cruz, Enrique M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744555/
https://www.ncbi.nlm.nih.gov/pubmed/26730886
http://dx.doi.org/10.1016/j.jmb.2015.12.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744555/
https://www.ncbi.nlm.nih.gov/pubmed/26730886
http://dx.doi.org/10.1016/j.jmb.2015.12.018

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