Cargando…
Synthesis and summary of patient‐reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery
AIM: Patient‐reported outcome (PRO) measures (PROMs) are standard measures in the assessment of colorectal cancer (CRC) treatment, but the range and complexity of available PROMs may be hindering the synthesis of evidence. This systematic review aimed to: (i) summarize PROMs in studies of CRC surger...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744711/ https://www.ncbi.nlm.nih.gov/pubmed/26058878 http://dx.doi.org/10.1111/codi.13021 |
_version_ | 1782414517189214208 |
---|---|
author | McNair, A. G. K. Whistance, R. N. Forsythe, R. O. Rees, J. Jones, J. E. Pullyblank, A. M. Avery, K. N. L. Brookes, S. T. Thomas, M. G. Sylvester, P. A. Russell, A. Oliver, A. Morton, D. Kennedy, R. Jayne, D. G. Huxtable, R. Hackett, R. Dutton, S. J. Coleman, M. G. Card, M. Brown, J. Blazeby, J. M. |
author_facet | McNair, A. G. K. Whistance, R. N. Forsythe, R. O. Rees, J. Jones, J. E. Pullyblank, A. M. Avery, K. N. L. Brookes, S. T. Thomas, M. G. Sylvester, P. A. Russell, A. Oliver, A. Morton, D. Kennedy, R. Jayne, D. G. Huxtable, R. Hackett, R. Dutton, S. J. Coleman, M. G. Card, M. Brown, J. Blazeby, J. M. |
author_sort | McNair, A. G. K. |
collection | PubMed |
description | AIM: Patient‐reported outcome (PRO) measures (PROMs) are standard measures in the assessment of colorectal cancer (CRC) treatment, but the range and complexity of available PROMs may be hindering the synthesis of evidence. This systematic review aimed to: (i) summarize PROMs in studies of CRC surgery and (ii) categorize PRO content to inform the future development of an agreed minimum ‘core’ outcome set to be measured in all trials. METHOD: All PROMs were identified from a systematic review of prospective CRC surgical studies. The type and frequency of PROMs in each study were summarized, and the number of items documented. All items were extracted and independently categorized by content by two researchers into ‘health domains’, and discrepancies were discussed with a patient and expert. Domain popularity and the distribution of items were summarized. RESULTS: Fifty‐eight different PROMs were identified from the 104 included studies. There were 23 generic, four cancer‐specific, 11 disease‐specific and 16 symptom‐specific questionnaires, and three ad hoc measures. The most frequently used PROM was the EORTC QLQ‐C30 (50 studies), and most PROMs (n = 40, 69%) were used in only one study. Detailed examination of the 50 available measures identified 917 items, which were categorized into 51 domains. The domains comprising the most items were ‘anxiety’ (n = 85, 9.2%), ‘fatigue’ (n = 67, 7.3%) and ‘physical function’ (n = 63, 6.9%). No domains were included in all PROMs. CONCLUSION: There is major heterogeneity of PRO measurement and a wide variation in content assessed in the PROMs available for CRC. A core outcome set will improve PRO outcome measurement and reporting in CRC trials. |
format | Online Article Text |
id | pubmed-4744711 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-47447112016-02-18 Synthesis and summary of patient‐reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery McNair, A. G. K. Whistance, R. N. Forsythe, R. O. Rees, J. Jones, J. E. Pullyblank, A. M. Avery, K. N. L. Brookes, S. T. Thomas, M. G. Sylvester, P. A. Russell, A. Oliver, A. Morton, D. Kennedy, R. Jayne, D. G. Huxtable, R. Hackett, R. Dutton, S. J. Coleman, M. G. Card, M. Brown, J. Blazeby, J. M. Colorectal Dis Systematic Review AIM: Patient‐reported outcome (PRO) measures (PROMs) are standard measures in the assessment of colorectal cancer (CRC) treatment, but the range and complexity of available PROMs may be hindering the synthesis of evidence. This systematic review aimed to: (i) summarize PROMs in studies of CRC surgery and (ii) categorize PRO content to inform the future development of an agreed minimum ‘core’ outcome set to be measured in all trials. METHOD: All PROMs were identified from a systematic review of prospective CRC surgical studies. The type and frequency of PROMs in each study were summarized, and the number of items documented. All items were extracted and independently categorized by content by two researchers into ‘health domains’, and discrepancies were discussed with a patient and expert. Domain popularity and the distribution of items were summarized. RESULTS: Fifty‐eight different PROMs were identified from the 104 included studies. There were 23 generic, four cancer‐specific, 11 disease‐specific and 16 symptom‐specific questionnaires, and three ad hoc measures. The most frequently used PROM was the EORTC QLQ‐C30 (50 studies), and most PROMs (n = 40, 69%) were used in only one study. Detailed examination of the 50 available measures identified 917 items, which were categorized into 51 domains. The domains comprising the most items were ‘anxiety’ (n = 85, 9.2%), ‘fatigue’ (n = 67, 7.3%) and ‘physical function’ (n = 63, 6.9%). No domains were included in all PROMs. CONCLUSION: There is major heterogeneity of PRO measurement and a wide variation in content assessed in the PROMs available for CRC. A core outcome set will improve PRO outcome measurement and reporting in CRC trials. John Wiley and Sons Inc. 2015-10-09 2015-11 /pmc/articles/PMC4744711/ /pubmed/26058878 http://dx.doi.org/10.1111/codi.13021 Text en ©2015 The Authors. Colorectal Disease published by John Wiley & Sons Ltd on behalf of Association of Coloproctology of Great Britain and Ireland. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Systematic Review McNair, A. G. K. Whistance, R. N. Forsythe, R. O. Rees, J. Jones, J. E. Pullyblank, A. M. Avery, K. N. L. Brookes, S. T. Thomas, M. G. Sylvester, P. A. Russell, A. Oliver, A. Morton, D. Kennedy, R. Jayne, D. G. Huxtable, R. Hackett, R. Dutton, S. J. Coleman, M. G. Card, M. Brown, J. Blazeby, J. M. Synthesis and summary of patient‐reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery |
title | Synthesis and summary of patient‐reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery |
title_full | Synthesis and summary of patient‐reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery |
title_fullStr | Synthesis and summary of patient‐reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery |
title_full_unstemmed | Synthesis and summary of patient‐reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery |
title_short | Synthesis and summary of patient‐reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery |
title_sort | synthesis and summary of patient‐reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744711/ https://www.ncbi.nlm.nih.gov/pubmed/26058878 http://dx.doi.org/10.1111/codi.13021 |
work_keys_str_mv | AT mcnairagk synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT whistancern synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT forsythero synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT reesj synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT jonesje synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT pullyblankam synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT averyknl synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT brookesst synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT thomasmg synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT sylvesterpa synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT russella synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT olivera synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT mortond synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT kennedyr synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT jaynedg synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT huxtabler synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT hackettr synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT duttonsj synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT colemanmg synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT cardm synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT brownj synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT blazebyjm synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery AT synthesisandsummaryofpatientreportedoutcomemeasurestoinformthedevelopmentofacoreoutcomesetincolorectalcancersurgery |