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In situ coating makes it easier for children to swallow and tolerate tablets and capsules
AIM: Getting children to swallow tablets and capsules is a challenge, and factors that influence their ability to swallow include taste, smell and texture. The aim of this study was to explore how well paediatric patients tolerated and accepted the MedCoat(®) in situ coating for tablets and capsules...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744733/ https://www.ncbi.nlm.nih.gov/pubmed/25982837 http://dx.doi.org/10.1111/apa.13041 |
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author | El Edelbi, R Eksborg, S Lindemalm, S |
author_facet | El Edelbi, R Eksborg, S Lindemalm, S |
author_sort | El Edelbi, R |
collection | PubMed |
description | AIM: Getting children to swallow tablets and capsules is a challenge, and factors that influence their ability to swallow include taste, smell and texture. The aim of this study was to explore how well paediatric patients tolerated and accepted the MedCoat(®) in situ coating for tablets and capsules. METHODS: A nonrandomised intervention study was performed at the Astrid Lindgren Children′s Hospital, Karolinska University Hospital, Sweden. We identified 78 paediatric patients, 43 females and 35 males, who had problems swallowing tablets and capsules and evaluated their abilities with questionnaires. The median age of the patients was nine years old, and the range was two to 17 years old. RESULTS: Swallowing ability and palatability was improved by in situ coating. The results showed that 66 of 77 paediatric patients (86%, 95% confidence interval: 76–93%) were able to take the drugs they had been prescribed after in situ coating. Swallowing improved in 87% of cases, and palatability improved in 85% of cases. CONCLUSION: A study of 77 paediatric patients with a median age of nine years, and a range of two to 17 years, found that 86% were able to take the tablets and capsules they had been prescribed after they were coated with the MedCoat. |
format | Online Article Text |
id | pubmed-4744733 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-47447332016-02-18 In situ coating makes it easier for children to swallow and tolerate tablets and capsules El Edelbi, R Eksborg, S Lindemalm, S Acta Paediatr Regular Articles AIM: Getting children to swallow tablets and capsules is a challenge, and factors that influence their ability to swallow include taste, smell and texture. The aim of this study was to explore how well paediatric patients tolerated and accepted the MedCoat(®) in situ coating for tablets and capsules. METHODS: A nonrandomised intervention study was performed at the Astrid Lindgren Children′s Hospital, Karolinska University Hospital, Sweden. We identified 78 paediatric patients, 43 females and 35 males, who had problems swallowing tablets and capsules and evaluated their abilities with questionnaires. The median age of the patients was nine years old, and the range was two to 17 years old. RESULTS: Swallowing ability and palatability was improved by in situ coating. The results showed that 66 of 77 paediatric patients (86%, 95% confidence interval: 76–93%) were able to take the drugs they had been prescribed after in situ coating. Swallowing improved in 87% of cases, and palatability improved in 85% of cases. CONCLUSION: A study of 77 paediatric patients with a median age of nine years, and a range of two to 17 years, found that 86% were able to take the tablets and capsules they had been prescribed after they were coated with the MedCoat. John Wiley and Sons Inc. 2015-06-09 2015-09 /pmc/articles/PMC4744733/ /pubmed/25982837 http://dx.doi.org/10.1111/apa.13041 Text en ©2015 The Authors. Acta Pædiatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Pædiatrica This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Regular Articles El Edelbi, R Eksborg, S Lindemalm, S In situ coating makes it easier for children to swallow and tolerate tablets and capsules |
title | In situ coating makes it easier for children to swallow and tolerate tablets and capsules |
title_full | In situ coating makes it easier for children to swallow and tolerate tablets and capsules |
title_fullStr | In situ coating makes it easier for children to swallow and tolerate tablets and capsules |
title_full_unstemmed | In situ coating makes it easier for children to swallow and tolerate tablets and capsules |
title_short | In situ coating makes it easier for children to swallow and tolerate tablets and capsules |
title_sort | in situ coating makes it easier for children to swallow and tolerate tablets and capsules |
topic | Regular Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744733/ https://www.ncbi.nlm.nih.gov/pubmed/25982837 http://dx.doi.org/10.1111/apa.13041 |
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