Cargando…

Ion mobility mass spectrometry enhances low-abundance species detection in untargeted lipidomics

We describe a simple method for the detection of low intensity lipid signals in complex tissue samples, based on a combination of liquid chromatography/mass spectrometry and ion mobility mass spectrometry. The method relies on visual and software-assisted analysis of overlapped mobilograms (diagrams...

Descripción completa

Detalles Bibliográficos
Autores principales:	Basit, Abdul, Pontis, Silvia, Piomelli, Daniele, Armirotti, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744830/ https://www.ncbi.nlm.nih.gov/pubmed/26900387 http://dx.doi.org/10.1007/s11306-016-0971-3

Ejemplares similares

Patch clamp-assisted single neuron lipidomics
por: Merrill, Collin B., et al.
Publicado: (2017)

Untargeted lipidomics using liquid chromatography-ion mobility-mass spectrometry reveals novel triacylglycerides in human milk
por: George, Alexandra D., et al.
Publicado: (2020)

Author Correction: Patch clamp-assisted single neuron lipidomics
por: Merrill, Collin B., et al.
Publicado: (2018)

Rapid evaluation of 25 key sphingolipids and phosphosphingolipids in human plasma by LC-MS/MS
por: Basit, Abdul, et al.
Publicado: (2015)

Volumetric Absorptive Microsampling of Blood for Untargeted Lipidomics
por: Marasca, Camilla, et al.
Publicado: (2021)

Towards Lipidomics of Low-Abundant Species for Exploring Tumor Heterogeneity Guided by High-Resolution Mass Spectrometry Imaging
por: Cimino, Jonathan, et al.
Publicado: (2013)

Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol
por: Zalloua, Pierre, et al.
Publicado: (2019)

Right in two: capabilities of ion mobility spectrometry for untargeted metabolomics
por: Moses, Tessa, et al.
Publicado: (2023)

Evaluating Software Tools for Lipid Identification from Ion Mobility Spectrometry–Mass Spectrometry Lipidomics Data
por: Ross, Dylan H., et al.
Publicado: (2023)

Single-cell lipidomics enabled by dual-polarity ionization and ion mobility-mass spectrometry imaging
por: Zhang, Hua, et al.
Publicado: (2023)

Lipidomic Characterization of Oocytes at Single-Cell Level Using Nanoflow Chromatography-Trapped Ion Mobility Spectrometry-Mass Spectrometry
por: Zhu, Pujia, et al.
Publicado: (2023)

Rapid HILIC-Z ion mobility mass spectrometry (RHIMMS) method for untargeted metabolomics of complex biological samples
por: Pičmanová, Martina, et al.
Publicado: (2022)

Mass spectrometry and multivariate analysis to classify cervical intraepithelial neoplasia from blood plasma: an untargeted lipidomic study
por: Neves, Ana C. O., et al.
Publicado: (2018)

An Untargeted Lipidomics Study of Acute Ischemic Stroke with Hyperglycemia Based on Ultrahigh-Performance Liquid Chromatography-Mass Spectrometry
por: Guo, Jia, et al.
Publicado: (2022)

Computational mass spectrometry accelerates C = C position-resolved untargeted lipidomics using oxygen attachment dissociation
por: Uchino, Haruki, et al.
Publicado: (2022)

A Novel Approach to Characterize the Lipidome of Marine Archaeon Nitrosopumilus maritimus by Ion Mobility Mass Spectrometry
por: Law, Kai P., et al.
Publicado: (2021)

Untargeted Lipidomics Method for the Discrimination of Five Crab Species by Ultra-High-Performance Liquid Chromatography High-Resolution Mass Spectrometry Combined with Chemometrics
por: Yao, Jiaxu, et al.
Publicado: (2023)

Combined hydrophilic interaction liquid chromatography-scanning field asymmetric waveform ion mobility spectrometry-time-of-flight mass spectrometry for untargeted metabolomics
por: Szykuła, Katarzyna M., et al.
Publicado: (2019)

Lipidomics of Environmental Microbial Communities. I: Visualization of Component Distributions Using Untargeted Analysis of High-Resolution Mass Spectrometry Data
por: Bale, Nicole J., et al.
Publicado: (2021)

HIGH RESOLUTION MASS SPECTROMETRY IN LIPIDOMICS
por: Züllig, Thomas, et al.
Publicado: (2020)

Optimization of Mobile Phase Modifiers for Fast LC-MS-Based Untargeted Metabolomics and Lipidomics
por: Cajka, Tomas, et al.
Publicado: (2023)

Targeted and Untargeted Mass Spectrometry-Based Metabolomics for Chemical Profiling of Three Coffee Species
por: Montis, Andrea, et al.
Publicado: (2022)

A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration
por: Palese, Francesca, et al.
Publicado: (2019)

Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts
por: Vasilopoulou, Catherine G., et al.
Publicado: (2020)

Investigation of Dendriplexes by Ion Mobility-Mass Spectrometry
por: Leriche, Emma-Dune, et al.
Publicado: (2014)

Developments in tandem ion mobility mass spectrometry
por: Eldrid, Charles, et al.
Publicado: (2020)

A mass spectrum-oriented computational method for ion mobility-resolved untargeted metabolomics
por: Luo, Mingdu, et al.
Publicado: (2023)

Untargeted Headspace-Gas Chromatography-Ion Mobility Spectrometry in Combination with Chemometrics for Detecting the Age of Chinese Liquor (Baijiu)
por: Chen, Shuang, et al.
Publicado: (2021)

Inborn Errors of Metabolism in the Era of Untargeted Metabolomics and Lipidomics
por: Ismail, Israa T, et al.
Publicado: (2019)

The Hitchhiker’s Guide to Untargeted Lipidomics Analysis: Practical Guidelines
por: Smirnov, Dmitrii, et al.
Publicado: (2021)

Untargeted Lipidomics of Erythrocytes under Simulated Microgravity Conditions
por: Manis, Cristina, et al.
Publicado: (2023)

Untargeted Lipidomics Study of Bipolar Disorder Patients in Serbia
por: Jadranin, Milka, et al.
Publicado: (2023)

Ion Mobility-Mass Spectrometry: Time-Dispersive Instrumentation
por: May, Jody C., et al.
Publicado: (2014)

Recommendations for reporting ion mobility Mass Spectrometry measurements
por: Gabelica, Valérie, et al.
Publicado: (2019)

Mass Spectrometry Based Lipidomics: An Overview of Technological Platforms
por: Köfeler, Harald C., et al.
Publicado: (2012)

Progress of Mass Spectrometry-Based Lipidomics in the Dairy Field
por: Ren, Wei, et al.
Publicado: (2023)

Untargeted lipidomic features associated with colorectal cancer in a prospective cohort
por: Perttula, Kelsi, et al.
Publicado: (2018)

Four-dimensional trapped ion mobility spectrometry lipidomics for high throughput clinical profiling of human blood samples
por: Lerner, Raissa, et al.
Publicado: (2023)

Plant lipidomics based on hydrophilic interaction chromatography coupled to ion trap time-of-flight mass spectrometry
por: Okazaki, Yozo, et al.
Publicado: (2011)

Mobility-Resolved Ion Selection in Uniform Drift Field Ion Mobility Spectrometry/Mass Spectrometry: Dynamic Switching in Structures for Lossless Ion Manipulations
por: Webb, Ian K., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ihtgldgbqufnoshf14g2tl1uhj