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Sustainability of Transient Kinetic Regimes and Origins of Death

It is generally recognized that a distinguishing feature of life is its peculiar capability to avoid equilibration. The origin of this capability and its evolution along the timeline of abiogenesis is not yet understood. We propose to study an analog of this phenomenon that could emerge in non-biolo...

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Autores principales: Zubarev, Dmitry Yu., Pachón, Leonardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744936/
https://www.ncbi.nlm.nih.gov/pubmed/26853459
http://dx.doi.org/10.1038/srep20562
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author Zubarev, Dmitry Yu.
Pachón, Leonardo A.
author_facet Zubarev, Dmitry Yu.
Pachón, Leonardo A.
author_sort Zubarev, Dmitry Yu.
collection PubMed
description It is generally recognized that a distinguishing feature of life is its peculiar capability to avoid equilibration. The origin of this capability and its evolution along the timeline of abiogenesis is not yet understood. We propose to study an analog of this phenomenon that could emerge in non-biological systems. To this end, we introduce the concept of sustainability of transient kinetic regimes. This concept is illustrated via investigation of cooperative effects in an extended system of compartmentalized chemical oscillators under batch and semi-batch conditions. The computational study of a model system shows robust enhancement of lifetimes of the decaying oscillations which translates into the evolution of the survival function of the transient non-equilibrium regime. This model does not rely on any form of replication. Rather, it explores the role of a structured effective environment as a contributor to the system-bath interactions that define non-equilibrium regimes. We implicate the noise produced by the effective environment of a compartmentalized oscillator as the cause of the lifetime extension.
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spelling pubmed-47449362016-02-16 Sustainability of Transient Kinetic Regimes and Origins of Death Zubarev, Dmitry Yu. Pachón, Leonardo A. Sci Rep Article It is generally recognized that a distinguishing feature of life is its peculiar capability to avoid equilibration. The origin of this capability and its evolution along the timeline of abiogenesis is not yet understood. We propose to study an analog of this phenomenon that could emerge in non-biological systems. To this end, we introduce the concept of sustainability of transient kinetic regimes. This concept is illustrated via investigation of cooperative effects in an extended system of compartmentalized chemical oscillators under batch and semi-batch conditions. The computational study of a model system shows robust enhancement of lifetimes of the decaying oscillations which translates into the evolution of the survival function of the transient non-equilibrium regime. This model does not rely on any form of replication. Rather, it explores the role of a structured effective environment as a contributor to the system-bath interactions that define non-equilibrium regimes. We implicate the noise produced by the effective environment of a compartmentalized oscillator as the cause of the lifetime extension. Nature Publishing Group 2016-02-08 /pmc/articles/PMC4744936/ /pubmed/26853459 http://dx.doi.org/10.1038/srep20562 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Zubarev, Dmitry Yu.
Pachón, Leonardo A.
Sustainability of Transient Kinetic Regimes and Origins of Death
title Sustainability of Transient Kinetic Regimes and Origins of Death
title_full Sustainability of Transient Kinetic Regimes and Origins of Death
title_fullStr Sustainability of Transient Kinetic Regimes and Origins of Death
title_full_unstemmed Sustainability of Transient Kinetic Regimes and Origins of Death
title_short Sustainability of Transient Kinetic Regimes and Origins of Death
title_sort sustainability of transient kinetic regimes and origins of death
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744936/
https://www.ncbi.nlm.nih.gov/pubmed/26853459
http://dx.doi.org/10.1038/srep20562
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