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Extracellular matrix stiffness dictates Wnt expression through integrin pathway

It is well established that extracellular matrix (ECM) stiffness plays a significant role in regulating the phenotypes and behaviors of many cell types. However, the mechanism underlying the sensing of mechanical cues and subsequent elasticity-triggered pathways remains largely unknown. We observed...

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Detalles Bibliográficos
Autores principales: Du, Jing, Zu, Yan, Li, Jing, Du, Shuyuan, Xu, Yipu, Zhang, Lang, Jiang, Li, Wang, Zhao, Chien, Shu, Yang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745056/
https://www.ncbi.nlm.nih.gov/pubmed/26854061
http://dx.doi.org/10.1038/srep20395