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Formyl-methionine as a degradation signal at the N-termini of bacterial proteins

In bacteria, all nascent proteins bear the pretranslationally formed N-terminal formyl-methionine (fMet) residue. The fMet residue is cotranslationally deformylated by a ribosome-associated deformylase. The formylation of N-terminal Met in bacterial proteins is not strictly essential for either tran...

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Detalles Bibliográficos
Autores principales: Piatkov, Konstantin I., Vu, Tri T. M., Hwang, Cheol-Sang, Varshavsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745127/
https://www.ncbi.nlm.nih.gov/pubmed/26866044
http://dx.doi.org/10.15698/mic2015.10.231