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Formyl-methionine as a degradation signal at the N-termini of bacterial proteins
In bacteria, all nascent proteins bear the pretranslationally formed N-terminal formyl-methionine (fMet) residue. The fMet residue is cotranslationally deformylated by a ribosome-associated deformylase. The formylation of N-terminal Met in bacterial proteins is not strictly essential for either tran...
Autores principales: | Piatkov, Konstantin I., Vu, Tri T. M., Hwang, Cheol-Sang, Varshavsky, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745127/ https://www.ncbi.nlm.nih.gov/pubmed/26866044 http://dx.doi.org/10.15698/mic2015.10.231 |
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