TGF-β and Hypoxia/Reoxygenation Promote Radioresistance of A549 Lung Cancer Cells through Activation of Nrf2 and EGFR

Although many studies have examined the roles of hypoxia and transforming growth factor- (TGF-) β separately in the tumor microenvironment, the effects of simultaneous treatment with hypoxia/reoxygenation and TGF-β on tumor malignancy are unclear. Here, we investigated the effects of redox signaling...

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Detalles Bibliográficos
Autores principales: Lee, Sae-lo-oom, Ryu, Hwani, Son, A-rang, Seo, Bitna, Kim, Jooyoung, Jung, Seung-Youn, Song, Jie-Young, Hwang, Sang-Gu, Ahn, Jiyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745286/
https://www.ncbi.nlm.nih.gov/pubmed/26904167
http://dx.doi.org/10.1155/2016/6823471

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