The Protective Effects of Isoliquiritigenin and Glycyrrhetinic Acid against Triptolide-Induced Oxidative Stress in HepG2 Cells Involve Nrf2 Activation

Triptolide (TP), an active ingredient of Tripterygium wilfordii Hook f., possesses a wide range of biological activities. Oxidative stress likely plays a role in TP-induced hepatotoxicity. Isoliquiritigenin (ISL) and glycyrrhetinic acid (GA) are potent hepatoprotection agents. The aim of the present...

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Detalles Bibliográficos
Autores principales: Cao, Ling-Juan, Li, Huan-De, Yan, Miao, Li, Zhi-Hua, Gong, Hui, Jiang, Pei, Deng, Yang, Fang, Ping-Fei, Zhang, Bi-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745288/
https://www.ncbi.nlm.nih.gov/pubmed/26904149
http://dx.doi.org/10.1155/2016/8912184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745288/
https://www.ncbi.nlm.nih.gov/pubmed/26904149
http://dx.doi.org/10.1155/2016/8912184

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