Cargando…

Urinary APE1/Ref-1: A Potential Bladder Cancer Biomarker

Bladder cancer (BCa) is one of the most common urothelial cancers with still noticeable incidence rate. Early detection of BCa is highly correlated with successful therapeutic outcomes. We previously showed that apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) was expressed at an inc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Sunga, Shin, Ju Hyun, Lee, Yu Ran, Joo, Hee Kyoung, Song, Ki Hak, Na, Yong Gil, Chang, Seok Jong, Lim, Jae Sung, Jeon, Byeong Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745317/ https://www.ncbi.nlm.nih.gov/pubmed/27057081 http://dx.doi.org/10.1155/2016/7276502

Ejemplares similares

Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target Protein
por: Choi, Sunga, et al.
Publicado: (2016)

Altered Secretory Activity of APE1/Ref-1 D148E Variants Identified in Human Patients With Bladder Cancer
por: Lee, Yu Ran, et al.
Publicado: (2016)

APE1/Ref-1 as a Serological Biomarker for the Detection of Bladder Cancer
por: Shin, Ju Hyun, et al.
Publicado: (2015)

ATP Binding Cassette Transporter A1 is Involved in Extracellular Secretion of Acetylated APE1/Ref-1
por: Lee, Yu Ran, et al.
Publicado: (2019)

Therapeutic positioning of secretory acetylated APE1/Ref-1 requirement for suppression of tumor growth in triple-negative breast cancer in vivo
por: Lee, Yu Ran, et al.
Publicado: (2018)

Dual Function of Secreted APE1/Ref-1 in TNBC Tumorigenesis: An Apoptotic Initiator and a Regulator of Chronic Inflammatory Signaling
por: Choi, Sunga, et al.
Publicado: (2022)

APE1/Ref-1 Inhibits Phosphate-Induced Calcification and Osteoblastic Phenotype Changes in Vascular Smooth Muscle Cells
por: Lee, Ki Mo, et al.
Publicado: (2017)

Extracellularly secreted APE1/Ref-1 triggers apoptosis in triple-negative breast cancer cells via RAGE binding, which is mediated through acetylation
por: Lee, Yu Ran, et al.
Publicado: (2015)

Secreted APE1/Ref-1 inhibits TNF-α-stimulated endothelial inflammation via thiol-disulfide exchange in TNF receptor
por: Park, Myoung Soo, et al.
Publicado: (2016)

Plasma APE1/Ref-1 Correlates with Atherosclerotic Inflammation in ApoE(−/−) Mice
por: Lee, Yu Ran, et al.
Publicado: (2020)

Elevation of Serum APE1/Ref-1 in Experimental Murine Myocarditis
por: Jin, Seon-Ah, et al.
Publicado: (2017)

APE1/Ref-1 Inhibits Adipogenic Transcription Factors during Adipocyte Differentiation in 3T3-L1 Cells
por: Lee, Eun-Ok, et al.
Publicado: (2023)

Elevated APE1/Ref-1 Levels of Synovial Fluids in Patients with Rheumatoid Arthritis: Reflection of Disease Activity
por: Yoo, In Seol, et al.
Publicado: (2021)

17β-Estradiol Increases APE1/Ref-1 Secretion in Vascular Endothelial Cells and Ovariectomized Mice: Involvement of Calcium-Dependent Exosome Pathway
por: Lee, Yu-Ran, et al.
Publicado: (2021)

APE1/Ref-1 Role in Inflammation and Immune Response
por: Oliveira, Thais Teixeira, et al.
Publicado: (2022)

APE1/Ref-1 as a Novel Target for Retinal Diseases
por: Heisel, Curtis, et al.
Publicado: (2021)

APE1/Ref-1 Regulates STAT3 Transcriptional Activity and APE1/Ref-1–STAT3 Dual-Targeting Effectively Inhibits Pancreatic Cancer Cell Survival
por: Cardoso, Angelo A., et al.
Publicado: (2012)

The role of APE/Ref-1 signaling pathway in hepatocellular carcinoma progression
por: YANG, ZHEN, et al.
Publicado: (2014)

APE1/Ref-1 as a Therapeutic Target for Inflammatory Bowel Disease
por: Sahakian, Lauren, et al.
Publicado: (2023)

New Horizons for the Roles and Association of APE1/Ref-1 and ABCA1 in Atherosclerosis
por: Chen, Wujun, et al.
Publicado: (2021)

Inhibition of APE1/Ref-1 for Neovascular Eye Diseases: From Biology to Therapy
por: Hartman, Gabriella D., et al.
Publicado: (2021)

Bis-Cinnamamide Derivatives as APE/Ref-1 Inhibitors for the Treatment of Human Melanoma
por: Alhazmi, Razan, et al.
Publicado: (2022)

Changes in the Plasma Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1(APE1/Ref-1) Level during Cancer Surgery: An Observational Study
por: Jo, Yumin, et al.
Publicado: (2021)

Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1)
por: Jackson, Elias B., et al.
Publicado: (2005)

DNA Repair and Cancer Therapy: Targeting APE1/Ref-1 Using Dietary Agents
por: Raffoul, Julian J., et al.
Publicado: (2012)

Identification of a novel potential antitumor activity of gossypol as an APE1/Ref-1 inhibitor
por: Qian, Chengyuan, et al.
Publicado: (2014)

APE1/Ref-1 – One Target with Multiple Indications: Emerging Aspects and New Directions
por: Mijit, Mahmut, et al.
Publicado: (2021)

Identification of Novel Pathways Regulated by APE1/Ref-1 in Human Retinal Endothelial Cells
por: Mijit, Mahmut, et al.
Publicado: (2023)

Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic
por: Shah, Fenil, et al.
Publicado: (2017)

Nitric oxide controls nuclear export of APE1/Ref-1 through S-nitrosation of Cysteines 93 and 310
por: Qu, Jing, et al.
Publicado: (2007)

APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions
por: Thakur, Shweta, et al.
Publicado: (2014)

Activation of NRF2 by APE1/REF1 is redox-dependent in Barrett's related esophageal adenocarcinoma cells
por: Sriramajayam, Kannappan, et al.
Publicado: (2021)

Resistance exercise training increase activation of AKT-eNOS and Ref-1 expression by FOXO-1 activation in aorta of F344 rats
por: Li, Meng, et al.
Publicado: (2015)

Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
por: Pines, Alex, et al.
Publicado: (2005)

Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis
por: Di Maso, Vittorio, et al.
Publicado: (2015)

Dual Regulatory Roles of Human AP-Endonuclease (APE1/Ref-1) in CDKN1A/p21 Expression
por: Sengupta, Shiladitya, et al.
Publicado: (2013)

Effects of gemcitabine on APE/ref-1 endonuclease activity in pancreatic cancer cells, and the therapeutic potential of antisense oligonucleotides
por: Lau, J P, et al.
Publicado: (2004)

Allopurinol Protects against Ischemia/Reperfusion-Induced Injury in Rat Urinary Bladders
por: Shin, Ju-Hyun, et al.
Publicado: (2015)

Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage
por: Zaky, Amira, et al.
Publicado: (2008)

Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function
por: Vascotto, Carlo, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_08b0tbravh2bnjp313hu84kmqd