Graves Disease Induced by Radioiodine Therapy for Toxic Nodular Goiter: A Case Report

Graves’ disease (GD) may be observed as an infrequent adverse effect after radioiodine therapy (RAIT) for toxic thyroid adenoma (TA) and toxic multi nodular goiter (MNG). We present a case of a 55-year-old male with a toxic nodule who was treated with RAI. After therapy, the patient’s serum free tri...

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Autores principales: Yürekli, Yakup, Cengiz, Arzu, Güney, Engin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745407/
https://www.ncbi.nlm.nih.gov/pubmed/27529890
http://dx.doi.org/10.4274/mirt.74046
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author Yürekli, Yakup
Cengiz, Arzu
Güney, Engin
author_facet Yürekli, Yakup
Cengiz, Arzu
Güney, Engin
author_sort Yürekli, Yakup
collection PubMed
description Graves’ disease (GD) may be observed as an infrequent adverse effect after radioiodine therapy (RAIT) for toxic thyroid adenoma (TA) and toxic multi nodular goiter (MNG). We present a case of a 55-year-old male with a toxic nodule who was treated with RAI. After therapy, the patient’s serum free triiodothyronine (fT3) and free thyroxine (fT4) levels gradually increased. Antithyroid peroxidase (TPOAb), antithyroglobulin (TgAb) and TSH-receptor antibodies (TRAb) were also positive. Thyroid scintigraphy revealed diffuse intense uptake after four months of RAIT. Radiation-induced GD should be considered in patients with aggravated hyperthyroidism 3-4 months after therapy.
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spelling pubmed-47454072016-02-18 Graves Disease Induced by Radioiodine Therapy for Toxic Nodular Goiter: A Case Report Yürekli, Yakup Cengiz, Arzu Güney, Engin Mol Imaging Radionucl Ther Case Report Graves’ disease (GD) may be observed as an infrequent adverse effect after radioiodine therapy (RAIT) for toxic thyroid adenoma (TA) and toxic multi nodular goiter (MNG). We present a case of a 55-year-old male with a toxic nodule who was treated with RAI. After therapy, the patient’s serum free triiodothyronine (fT3) and free thyroxine (fT4) levels gradually increased. Antithyroid peroxidase (TPOAb), antithyroglobulin (TgAb) and TSH-receptor antibodies (TRAb) were also positive. Thyroid scintigraphy revealed diffuse intense uptake after four months of RAIT. Radiation-induced GD should be considered in patients with aggravated hyperthyroidism 3-4 months after therapy. Galenos Publishing 2015-10 2015-11-02 /pmc/articles/PMC4745407/ /pubmed/27529890 http://dx.doi.org/10.4274/mirt.74046 Text en © Molecular Imaging and Radionuclide Therapy, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yürekli, Yakup
Cengiz, Arzu
Güney, Engin
Graves Disease Induced by Radioiodine Therapy for Toxic Nodular Goiter: A Case Report
title Graves Disease Induced by Radioiodine Therapy for Toxic Nodular Goiter: A Case Report
title_full Graves Disease Induced by Radioiodine Therapy for Toxic Nodular Goiter: A Case Report
title_fullStr Graves Disease Induced by Radioiodine Therapy for Toxic Nodular Goiter: A Case Report
title_full_unstemmed Graves Disease Induced by Radioiodine Therapy for Toxic Nodular Goiter: A Case Report
title_short Graves Disease Induced by Radioiodine Therapy for Toxic Nodular Goiter: A Case Report
title_sort graves disease induced by radioiodine therapy for toxic nodular goiter: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745407/
https://www.ncbi.nlm.nih.gov/pubmed/27529890
http://dx.doi.org/10.4274/mirt.74046
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