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A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745425/ https://www.ncbi.nlm.nih.gov/pubmed/27019580 http://dx.doi.org/10.1155/2015/213236 |
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author | He, Fan Hua, Lu Gao, Li-jian |
author_facet | He, Fan Hua, Lu Gao, Li-jian |
author_sort | He, Fan |
collection | PubMed |
description | Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was assumed to be laminar, Newtonian, viscous, and incompressible. The vessel wall was assumed to be linear elastic, isotropic, and incompressible. The fluid-wall interaction scheme was constructed using the finite element method. Results. The results show that there are identical wall shear stress waveforms, wall stress, and strain waveforms at different locations. The comparison of the results demonstrates that wall shear stresses and wall strains are higher while wall stresses are lower at the more compliant section. The differences promote the probability of intimal thickening at some locations. Conclusions. The model is effective and gives satisfactory results. It could be extended to all kinds of arteries with complicated geometrical and material factors. |
format | Online Article Text |
id | pubmed-4745425 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-47454252016-03-27 A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch He, Fan Hua, Lu Gao, Li-jian Appl Bionics Biomech Research Article Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was assumed to be laminar, Newtonian, viscous, and incompressible. The vessel wall was assumed to be linear elastic, isotropic, and incompressible. The fluid-wall interaction scheme was constructed using the finite element method. Results. The results show that there are identical wall shear stress waveforms, wall stress, and strain waveforms at different locations. The comparison of the results demonstrates that wall shear stresses and wall strains are higher while wall stresses are lower at the more compliant section. The differences promote the probability of intimal thickening at some locations. Conclusions. The model is effective and gives satisfactory results. It could be extended to all kinds of arteries with complicated geometrical and material factors. Hindawi Publishing Corporation 2015 2015-03-16 /pmc/articles/PMC4745425/ /pubmed/27019580 http://dx.doi.org/10.1155/2015/213236 Text en Copyright © 2015 Fan He et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article He, Fan Hua, Lu Gao, Li-jian A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title | A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title_full | A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title_fullStr | A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title_full_unstemmed | A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title_short | A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title_sort | computational model for biomechanical effects of arterial compliance mismatch |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745425/ https://www.ncbi.nlm.nih.gov/pubmed/27019580 http://dx.doi.org/10.1155/2015/213236 |
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