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A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch

Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was a...

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Detalles Bibliográficos
Autores principales: He, Fan, Hua, Lu, Gao, Li-jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745425/
https://www.ncbi.nlm.nih.gov/pubmed/27019580
http://dx.doi.org/10.1155/2015/213236
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author He, Fan
Hua, Lu
Gao, Li-jian
author_facet He, Fan
Hua, Lu
Gao, Li-jian
author_sort He, Fan
collection PubMed
description Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was assumed to be laminar, Newtonian, viscous, and incompressible. The vessel wall was assumed to be linear elastic, isotropic, and incompressible. The fluid-wall interaction scheme was constructed using the finite element method. Results. The results show that there are identical wall shear stress waveforms, wall stress, and strain waveforms at different locations. The comparison of the results demonstrates that wall shear stresses and wall strains are higher while wall stresses are lower at the more compliant section. The differences promote the probability of intimal thickening at some locations. Conclusions. The model is effective and gives satisfactory results. It could be extended to all kinds of arteries with complicated geometrical and material factors.
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spelling pubmed-47454252016-03-27 A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch He, Fan Hua, Lu Gao, Li-jian Appl Bionics Biomech Research Article Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was assumed to be laminar, Newtonian, viscous, and incompressible. The vessel wall was assumed to be linear elastic, isotropic, and incompressible. The fluid-wall interaction scheme was constructed using the finite element method. Results. The results show that there are identical wall shear stress waveforms, wall stress, and strain waveforms at different locations. The comparison of the results demonstrates that wall shear stresses and wall strains are higher while wall stresses are lower at the more compliant section. The differences promote the probability of intimal thickening at some locations. Conclusions. The model is effective and gives satisfactory results. It could be extended to all kinds of arteries with complicated geometrical and material factors. Hindawi Publishing Corporation 2015 2015-03-16 /pmc/articles/PMC4745425/ /pubmed/27019580 http://dx.doi.org/10.1155/2015/213236 Text en Copyright © 2015 Fan He et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
He, Fan
Hua, Lu
Gao, Li-jian
A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title_full A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title_fullStr A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title_full_unstemmed A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title_short A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title_sort computational model for biomechanical effects of arterial compliance mismatch
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745425/
https://www.ncbi.nlm.nih.gov/pubmed/27019580
http://dx.doi.org/10.1155/2015/213236
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