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Primary Vaginal Non-Hodgkin’s Lymphoma: Report of a Rare Clinical Entity

A 52-year-old woman was referred to the gynecology outpatient clinic with a 2 months history of vaginal bleeding with intercourse, and no other symptoms. Vaginal examination revealed a firm, non-tender, mass in the posterior vaginal wall. The initial clinical impression was that of a vaginal carcino...

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Detalles Bibliográficos
Autores principales: Silva, Vera, Correia, Paulo, Oliveira, Nuno, Sá, Luís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745599/
https://www.ncbi.nlm.nih.gov/pubmed/26918105
http://dx.doi.org/10.4081/cp.2015.821
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author Silva, Vera
Correia, Paulo
Oliveira, Nuno
Sá, Luís
author_facet Silva, Vera
Correia, Paulo
Oliveira, Nuno
Sá, Luís
author_sort Silva, Vera
collection PubMed
description A 52-year-old woman was referred to the gynecology outpatient clinic with a 2 months history of vaginal bleeding with intercourse, and no other symptoms. Vaginal examination revealed a firm, non-tender, mass in the posterior vaginal wall. The initial clinical impression was that of a vaginal carcinoma and a biopsy under local anesthesia was performed, but the result was inconclusive. A deeper biopsy, under general anesthesia, was performed and a histological diagnosis of non-Hodgkin’s lymphoma was done. The staging workup permitted to exclude any other site of the body affected by the malignancy. Hematologists reviewed the patient and recommended chemotherapy. A complete tumor regression was observed and the patient has now a disease-free survival of 72 months. This case report intends to create awareness of this rare clinical entity. Although the gynecologist will rarely be faced to extranodal lymphoma, it should be included in the differential diagnosis of gynecologic malignancies.
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spelling pubmed-47455992016-02-25 Primary Vaginal Non-Hodgkin’s Lymphoma: Report of a Rare Clinical Entity Silva, Vera Correia, Paulo Oliveira, Nuno Sá, Luís Clin Pract Case Report A 52-year-old woman was referred to the gynecology outpatient clinic with a 2 months history of vaginal bleeding with intercourse, and no other symptoms. Vaginal examination revealed a firm, non-tender, mass in the posterior vaginal wall. The initial clinical impression was that of a vaginal carcinoma and a biopsy under local anesthesia was performed, but the result was inconclusive. A deeper biopsy, under general anesthesia, was performed and a histological diagnosis of non-Hodgkin’s lymphoma was done. The staging workup permitted to exclude any other site of the body affected by the malignancy. Hematologists reviewed the patient and recommended chemotherapy. A complete tumor regression was observed and the patient has now a disease-free survival of 72 months. This case report intends to create awareness of this rare clinical entity. Although the gynecologist will rarely be faced to extranodal lymphoma, it should be included in the differential diagnosis of gynecologic malignancies. PAGEPress Publications, Pavia, Italy 2015-12-22 /pmc/articles/PMC4745599/ /pubmed/26918105 http://dx.doi.org/10.4081/cp.2015.821 Text en ©Copyright V. Silva et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Silva, Vera
Correia, Paulo
Oliveira, Nuno
Sá, Luís
Primary Vaginal Non-Hodgkin’s Lymphoma: Report of a Rare Clinical Entity
title Primary Vaginal Non-Hodgkin’s Lymphoma: Report of a Rare Clinical Entity
title_full Primary Vaginal Non-Hodgkin’s Lymphoma: Report of a Rare Clinical Entity
title_fullStr Primary Vaginal Non-Hodgkin’s Lymphoma: Report of a Rare Clinical Entity
title_full_unstemmed Primary Vaginal Non-Hodgkin’s Lymphoma: Report of a Rare Clinical Entity
title_short Primary Vaginal Non-Hodgkin’s Lymphoma: Report of a Rare Clinical Entity
title_sort primary vaginal non-hodgkin’s lymphoma: report of a rare clinical entity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745599/
https://www.ncbi.nlm.nih.gov/pubmed/26918105
http://dx.doi.org/10.4081/cp.2015.821
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