PDGF upregulates CLEC-2 to induce T regulatory cells

The effect of platelet derived growth factor (PDGF) on immune cells is not elucidated. Here, we demonstrate PDGF inhibited the maturation of human DCs and induced IL-10 secretion. Culture of PDGF-DCs with T cells induced the polarization of T cells towards FoxP3 expressing T regulatory cells that se...

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Detalles Bibliográficos
Autores principales: Agrawal, Sudhanshu, Ganguly, Sreerupa, Hajian, Pega, Cao, Jia-Ning, Agrawal, Anshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745681/
https://www.ncbi.nlm.nih.gov/pubmed/26416420

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