Cargando…
A genome wide transcriptional model of the complex response to pre-TCR signalling during thymocyte differentiation
Developing thymocytes require pre-TCR signalling to differentiate from CD4−CD8− double negative to CD4+CD8+ double positive cell. Here we followed the transcriptional response to pre-TCR signalling in a synchronised population of differentiating double negative thymocytes. This time series analysis...
Autores principales: | Sahni, Hemant, Ross, Susan, Barbarulo, Alessandro, Solanki, Anisha, Lau, Ching-In, Furmanski, Anna, Saldaña, José Ignacio, Ono, Masahiro, Hubank, Mike, Barenco, Martino, Crompton, Tessa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745683/ https://www.ncbi.nlm.nih.gov/pubmed/26415229 |
Ejemplares similares
-
The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity
por: Furmanski, Anna L., et al.
Publicado: (2015) -
Sonic Hedgehog regulates thymic epithelial cell differentiation
por: Saldaña, José Ignacio, et al.
Publicado: (2016) -
IFITM proteins drive type 2 T helper cell differentiation and exacerbate allergic airway inflammation
por: Yánez, Diana C., et al.
Publicado: (2018) -
The kinesin motor protein Kif7 is required for T-cell development and normal MHC expression on thymic epithelial cells (TEC) in the thymus
por: Lau, Ching-In, et al.
Publicado: (2017) -
Hedgehog Signalling in the Embryonic Mouse Thymus
por: Barbarulo, Alessandro, et al.
Publicado: (2016)