Cargando…

Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity

Correction of human myeloid cell function is crucial for the prevention of inflammatory and allergic reactions as well as leukaemia progression. Caffeine, a naturally occurring food component, is known to display anti-inflammatory effects which have previously been ascribed largely to its inhibitory...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gibbs, Bernhard F., Silva, Isabel Gonçalves, Prokhorov, Alexandr, Abooali, Maryam, Yasinska, Inna M., Casely-Hayford, Maxwell A., Berger, Steffen M., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745685/ https://www.ncbi.nlm.nih.gov/pubmed/26384306

Ejemplares similares

Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function
por: Abooali, Maryam, et al.
Publicado: (2014)

Mitochondrial Defunctionalization Supresses Tim-3-Galectin-9 Secretory Pathway in Human Colorectal Cancer Cells and Thus Can Possibly Affect Tumor Immune Escape
por: Sakhnevych, Svetlana S., et al.
Publicado: (2019)

Activation of immune evasion machinery is a part of the process of malignant transformation of human cells
por: Abooali, Maryam, et al.
Publicado: (2023)

L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytes
por: Schlichtner, Stephanie, et al.
Publicado: (2023)

Ligand-Receptor Interactions of Galectin-9 and VISTA Suppress Human T Lymphocyte Cytotoxic Activity
por: Yasinska, Inna M., et al.
Publicado: (2020)

Editorial: Pathological reactions of cytotoxic lymphoid cells as universal therapeutic targets in cancer and autoimmune disease
por: Sumbayev, Vadim V., et al.
Publicado: (2023)

129 Involvement of the Hypoxia-Inducible Factor-1 Transcription Complex in the Inflammatory Responses of Human Mast Cells and Basophils
por: Yasinska, Inna, et al.
Publicado: (2012)

61 Hypoxia-Inducible Factor 1 (HIF-1) Transcription is a “Signalling Driver” for Allergic Inflammation, Host Innate Immune Defence and Leukaemia Progression
por: Sumbayev, Vadim, et al.
Publicado: (2012)

T lymphocytes induce human cancer cells derived from solid malignant tumors to secrete galectin-9 which facilitates immunosuppression in cooperation with other immune checkpoint proteins
por: Schlichtner, Stephanie, et al.
Publicado: (2023)

Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 – Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes
por: Schlichtner, Stephanie, et al.
Publicado: (2022)

High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells
por: Teo Hansen Selnø, Anette, et al.
Publicado: (2021)

Nitric Oxide Activates Apoptosis Signal - Regulating Kinase 1 (ASK 1) Forming S-Nitrosothiols with Reactive Thioredoxin SH-Groups. Nitric Oxide Synthase (NOS) Induction Mediated Inhibition of Poly-(ADP-RIBOSE)-Polymerase (PARP) and Protein Kinase C (PKC) Activities as well as Intranucleosomal DNA Fragmentation (IDF) Increase in the HEP-2 Cells
por: Sumbayev, Vadim V., et al.
Publicado: (2001)

Alliance of galectin-3 and CD74 biochemical networks as a crucial component of survival machinery operated by human acute myeloid leukaemia cells
por: Yasinska, Inna M., et al.
Publicado: (2019)

Effects of Stem Cell Factor on Hypoxia-Inducible Factor 1 Alpha Accumulation in Human Acute Myeloid Leukaemia and LAD2 Mast Cells
por: Gibbs, Bernhard F., et al.
Publicado: (2011)

High mobility group box 1 (HMGB1) acts as an “alarmin” to promote acute myeloid leukaemia progression
por: Yasinska, Inna M., et al.
Publicado: (2018)

Involvement of Hypoxia-Inducible Factor-1 in the Inflammatory Responses of Human LAD2 Mast Cells and Basophils
por: Sumbayev, Vadim V., et al.
Publicado: (2012)

The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells
por: Gonçalves Silva, Isabel, et al.
Publicado: (2017)

Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells
por: Selnø, Anette Teo Hansen, et al.
Publicado: (2020)

Targeting of Basophil and Mast Cell Pro-Allergic Reactivity Using Functionalised Gold Nanoparticles
por: Yasinska, Inna M., et al.
Publicado: (2019)

Xanthine oxidase inhibitors and sepsis
por: Ramos, Maria Fátima de Paula, et al.
Publicado: (2018)

The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells
por: Gonçalves Silva, Isabel, et al.
Publicado: (2016)

Macrophage Differentiation and Polarization Regulate the Release of the Immune Checkpoint Protein V-Domain Ig Suppressor of T Cell Activation
por: Noubissi Nzeteu, Gaetan Aime, et al.
Publicado: (2022)

XANTHINE OXIDASE ACTIVITY IN REGENERATING LIVER
por: Feigelson, Muriel, et al.
Publicado: (1957)

Study of Drug Metabolism by Xanthine Oxidase
por: Zhao, Jing, et al.
Publicado: (2012)

Xanthine Oxidase—A Personal History
por: Hille, Russ
Publicado: (2023)

Xanthine oxidase and aldehyde oxidase contribute to allopurinol metabolism in rats
por: Tayama, Yoshitaka, et al.
Publicado: (2022)

The mechanism and significance of the conversion of xanthine dehydrogenase to xanthine oxidase in mammalian secretory gland cells
por: Kusano, Teruo, et al.
Publicado: (2022)

Xanthine Oxidase and Uric Acid in Atrial Fibrillation
por: Korantzopoulos, Panagiotis, et al.
Publicado: (2012)

The impact of xanthine oxidase (XO) on hemolytic diseases
por: Schmidt, Heidi M., et al.
Publicado: (2018)

Renoprotective Effect of Xanthine Oxidase Inhibitor, Topiroxostat
por: Katsuyama, Hisayuki, et al.
Publicado: (2019)

Xanthine oxidase inhibitors in ischaemic heart disease
por: Zdrenghea, Mihnea, et al.
Publicado: (2017)

The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer
por: Yasinska, Inna M., et al.
Publicado: (2019)

Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells
por: Sumbayev, Vadim V., et al.
Publicado: (2016)

Conversion of xanthine dehydrogenase to xanthine oxidase as a possible marker for hypoxia in tumours and normal tissues.
por: Anderson, R. F., et al.
Publicado: (1989)

Inhibition of Xanthine Oxidase-Catalyzed Xanthine and 6-Mercaptopurine Oxidation by Flavonoid Aglycones and Some of Their Conjugates
por: Mohos, Violetta, et al.
Publicado: (2020)

Xanthine oxidase acitivity in progressive spontaneous mammary carcinogenesis.
por: Sheth, N. A., et al.
Publicado: (1968)

Structure–Activity Relationship of Xanthones as Inhibitors of Xanthine Oxidase
por: Zhou, Ling-Yun, et al.
Publicado: (2018)

Side Effects and Interactions of the Xanthine Oxidase Inhibitor Febuxostat
por: Jordan, Andreas, et al.
Publicado: (2018)

Implication of changes in xanthine oxidase activity following hemodialysis
por: Fujioka, Hayato, et al.
Publicado: (2023)

Effect of caffeine and other xanthines on liver sinusoidal endothelial cell ultrastructure
por: Mao, Hong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kcqlaauhjqgtii88mreti04ces