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Vav1: A Dr. Jekyll and Mr. Hyde protein – good for the hematopoietic system, bad for cancer
Many deregulated signal transducer proteins are involved in various cancers at numerous stages of tumor development. One of these, Vav1, is normally expressed exclusively in the hematopoietic system, where it functions as a specific GDP/GTP nucleotide exchange factor (GEF), strictly regulated by tyr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745688/ https://www.ncbi.nlm.nih.gov/pubmed/26353933 |