New therapeutic strategies in neuroblastoma: combined targeting of a novel tyrosine kinase inhibitor and liposomal siRNAs against ALK

Many different aberrations in the Anaplastic Lymphoma Kinase (ALK) were found to be oncogenic drivers in several cancers including neuroblastoma (NB), therefore ALK is now considered a critical player in NB oncogenesis and a promising therapeutic target. The ALK-inhibitor crizotinib has a limited ac...

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Detalles Bibliográficos
Autores principales: Di Paolo, Daniela, Yang, D., Pastorino, Fabio, Emionite, Laura, Cilli, Michele, Daga, Antonio, Destefanis, Elisa, Di Fiore, Annarita, Piaggio, Francesca, Brignole, Chiara, Xu, Xiaobao, Liang, Chris, Gibbons, James, Ponzoni, Mirco, Perri, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745691/
https://www.ncbi.nlm.nih.gov/pubmed/26299615

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