A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme

The blossom of immunotherapy in melanoma highlights the need to delineate mechanisms of immune resistance. Recently, we have demonstrated that the RNA editing protein, adenosine deaminase acting on RNA-1 (ADAR1) is down-regulated during metastatic transition of melanoma, which enhances melanoma cell...

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Detalles Bibliográficos
Autores principales: Galore-Haskel, Gilli, Nemlich, Yael, Greenberg, Eyal, Ashkenazi, Shira, Hakim, Motti, Itzhaki, Orit, Shoshani, Noa, Shapira-Fromer, Ronnie, Ben-Ami, Eytan, Ofek, Efrat, Anafi, Liat, Besser, Michal J., Schachter, Jacob, Markel, Gal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745707/
https://www.ncbi.nlm.nih.gov/pubmed/26338962

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