Chromosomal catastrophe is a frequent event in clinically insignificant prostate cancer

Massive genomic rearrangements, a result of single catastrophic event termed chromothrispsis or chromosomal catastrophe, have been identified in a variety of human cancers. In a few cancer types, chromothripsis was found to be associated with poor prognosis. We performed mate-pair sequencing and ana...

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Detalles Bibliográficos
Autores principales: Kovtun, Irina V., Murphy, Stephen J., Johnson, Sarah H., Cheville, John C., Vasmatzis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745713/
https://www.ncbi.nlm.nih.gov/pubmed/26337081

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