miR-155, identified as anti-metastatic by global miRNA profiling of a metastasis model, inhibits cancer cell extravasation and colonization in vivo and causes significant signaling alterations

To gain insight into miRNA regulation in metastasis formation, we used a metastasis cell line model that allows investigation of extravasation and colonization of circulating cancer cells to lungs in mice. Using global miRNA profiling, 28 miRNAs were found to exhibit significantly altered expression...

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Detalles Bibliográficos
Autores principales: Thomsen, Karina G., Terp, Mikkel G., Lund, Rikke R., Søkilde, Rolf, Elias, Daniel, Bak, Martin, Litman, Thomas, Beck, Hans C., Lyng, Maria B., Ditzel, Henrik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745722/
https://www.ncbi.nlm.nih.gov/pubmed/26317550

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