Cargando…
Anti-angiogenic efficacy of 5′-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs
Short interfering RNA (siRNA) targeting angiogenic factors and further inhibiting tumor angiogenesis, is one of the potent antitumor candidates for lung cancer treatment. However, this strategy must be combined with other therapeutics like chemotherapy. In this study, we designed a 5′-triphosphate s...
Autores principales: | Yuan, Dongmei, Xia, Mao, Meng, Gang, Xu, Chun, Song, Yong, Wei, Jiwu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745754/ https://www.ncbi.nlm.nih.gov/pubmed/26336994 |
Ejemplares similares
-
Breaking tumor-induced immunosuppression with 5′-triphosphate siRNA silencing TGFβ and activating RIG-I
por: Schnurr, Max, et al.
Publicado: (2013) -
DUSP11-mediated control of 5′-triphosphate RNA regulates RIG-I sensitivity
por: Choi, Joon H., et al.
Publicado: (2020) -
Low-weight polyethylenimine cross-linked 2-hydroxypopyl-β-cyclodextrin and folic acid as an efficient and nontoxic siRNA carrier for gene silencing and tumor inhibition by VEGF siRNA
por: Li, Jin-Ming, et al.
Publicado: (2013) -
Inhibition of retinal neovascularization by siRNA targeting VEGF(165)
por: Xia, Xiao-bo, et al.
Publicado: (2008) -
Therapeutic siRNA silencing in inflammatory monocytes
por: Leuschner, Florian, et al.
Publicado: (2011)