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Heat shock factor 1, an inhibitor of non-homologous end joining repair

A novel role for HSF1 as an inhibitor of non-homologous end joining (NHEJ) repair activity was identified. HSF1 interacted directly with both of the N-terminal sequences of the Ku70 and Ku86 proteins, which inhibited the endogenous heterodimeric interaction between Ku70 and Ku86. The blocking of the...

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Detalles Bibliográficos
Autores principales:	Kang, Ga-Young, Kim, Eun-Ho, Lee, Hae-June, Gil, Na-Yeon, Cha, Hyuk-Jin, Lee, Yun-Sil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745757/ https://www.ncbi.nlm.nih.gov/pubmed/26359349

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