Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention

Cancer-associated fibroblasts (CAFs) constitute an important part of the tumor microenvironment and promote invasion via paracrine functions and physical impact on the tumor. Although the importance of including CAFs into three-dimensional (3D) cell cultures has been acknowledged, computational supp...

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Detalles Bibliográficos
Autores principales: Åkerfelt, Malin, Bayramoglu, Neslihan, Robinson, Sean, Toriseva, Mervi, Schukov, Hannu-Pekka, Härmä, Ville, Virtanen, Johannes, Sormunen, Raija, Kaakinen, Mika, Kannala, Juho, Eklund, Lauri, Heikkilä, Janne, Nees, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745780/
https://www.ncbi.nlm.nih.gov/pubmed/26375443

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