Cargando…
Identification of therapeutic targets in ovarian cancer through active tyrosine kinase profiling
The activation status of a set of pro-oncogenic tyrosine kinases in ovarian cancer patient samples was analyzed to define potential therapeutic targets. Frequent activation of HER family receptor tyrosine kinases, especially HER2, was observed. Studies in ovarian cancer cell lines confirmed the acti...
Autores principales: | Montero, Juan Carlos, García-Alonso, Sara, Ocaña, Alberto, Pandiella, Atanasio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745781/ https://www.ncbi.nlm.nih.gov/pubmed/26336133 |
Ejemplares similares
-
Regulation of the prometastatic neuregulin–MMP13 axis by SRC family kinases: therapeutic implications
por: Orive‐Ramos, Ana, et al.
Publicado: (2017) -
Expression of Erk5 in Early Stage Breast Cancer and Association with Disease Free Survival Identifies this Kinase as a Potential Therapeutic Target
por: Montero, Juan Carlos, et al.
Publicado: (2009) -
Multisite phosphorylation of P-Rex1 by protein kinase C
por: Montero, Juan Carlos, et al.
Publicado: (2016) -
Altered proTGFα/cleaved TGFα ratios offer new therapeutic strategies in renal carcinoma
por: García-Alonso, Sara, et al.
Publicado: (2021) -
Phospho-kinase profile of triple negative breast cancer and androgen receptor signaling
por: Cuenca-López, María D, et al.
Publicado: (2014)