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Histidine-rich glycoprotein function in hepatocellular carcinoma depends on its N-glycosylation status, and it regulates cell proliferation by inhibiting Erk1/2 phosphorylation

Hepatocellular carcinoma (HCC) is the third most common cause of cancer mortality. Significantly downregulated histidine-rich glycoprotein (HRG) during the dynamic stages (WB, WB7, and WB11) of neoplastic transformation of WB F344 hepatic oval-like cells was screened out by iTRAQ labeling followed b...

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Detalles Bibliográficos
Autores principales: Zhang, Qinle, Jiang, Kai, Li, Yan, Gao, Dongmei, Sun, Lu, Zhang, Shu, Liu, Tianhua, Guo, Kun, Liu, Yinkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745792/
https://www.ncbi.nlm.nih.gov/pubmed/26336134