LDL suppresses angiogenesis through disruption of the HIF pathway via NF-κB inhibition which is reversed by the proteasome inhibitor BSc2118

Since disturbance of angiogenesis predisposes to ischemic injuries, attempts to promote angiogenesis have been made to improve clinical outcomes of patients with many ischemic disorders. While hypoxia inducible factors (HIFs) stimulate vascular remodeling and angiogenesis, hyperlipidemia impairs ang...

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Detalles Bibliográficos
Autores principales: Yao, Gang, Zhang, Qi, Doeppner, Thorsten R., Niu, Feng, Li, Qiaochuan, Yang, Yanping, Kuckelkorn, Ulrike, Hagemann, Nina, Li, Wei, Hermann, Dirk M., Dai, Yun, Zhou, Wen, Jin, Fengyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745795/
https://www.ncbi.nlm.nih.gov/pubmed/26388611

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