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Efficient inhibition of ovarian cancer by degradable nanoparticle-delivered survivin T34A gene

Gene therapy has promising applications in ovarian cancer therapy. Blocking the function of the survivin protein could lead to the growth inhibition of cancer cells. Herein, we used degradable heparin–polyethyleneimine (HPEI) nanoparticles to deliver a dominant-negative human survivin T34A (hs-T34A)...

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Detalles Bibliográficos
Autores principales:	Luo, Li, Du, Ting, Zhang, Jiumeng, Zhao, Wei, Cheng, Hao, Yang, Yuping, Wu, Yujiao, Wang, Chunmei, Men, Ke, Gou, Maling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745847/ https://www.ncbi.nlm.nih.gov/pubmed/26893558 http://dx.doi.org/10.2147/IJN.S93496

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