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Potassium-3-beta-hydroxy-20-oxopregn-5-en-17-alpha-yl sulfate: a novel inhibitor of 78 kDa glucose-regulated protein

BACKGROUND: Previous studies have shown the central role of 78 kDa glucose-regulated protein (GRP78) in colorectal cancer (CRC) survival and chemoresistance. In the present study, we aimed to design a GRP78 inhibitor and test its potential to inhibit CRC cells growth. MATERIALS AND METHODS: Computer...

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Detalles Bibliográficos
Autores principales:	Mhaidat, Nizar M, Al-Balas, Qosay A, Alzoubi, Karem H, AlEjielat, Rowan F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745961/ https://www.ncbi.nlm.nih.gov/pubmed/26893572 http://dx.doi.org/10.2147/OTT.S97328

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