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By Regulating Mitochondrial Ca(2+)-Uptake UCP2 Modulates Intracellular Ca(2+)
INTRODUCTION: The possible role of UCP2 in modulating mitochondrial Ca(2+)-uptake (mCa(2+)-uptake) via the mitochondrial calcium uniporter (MCU) is highly controversial. METHODS: Thus, we analyzed mCa(2+)-uptake in isolated cardiac mitochondria, MCU single-channel activity in cardiac mitoplasts, dua...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746117/ https://www.ncbi.nlm.nih.gov/pubmed/26849136 http://dx.doi.org/10.1371/journal.pone.0148359 |