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In silico Analysis of HIV-1 Env-gp120 Reveals Structural Bases for Viral Adaptation in Growth-Restrictive Cells
Variable V1/V2 and V3 loops on human immunodeficiency virus type 1 (HIV-1) envelope-gp120 core play key roles in modulating viral competence to recognize two infection receptors, CD4 and chemokine-receptors. However, molecular bases for the modulation largely remain unclear. To address these issues,...
Autores principales: | Yokoyama, Masaru, Nomaguchi, Masako, Doi, Naoya, Kanda, Tadahito, Adachi, Akio, Sato, Hironori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746247/ https://www.ncbi.nlm.nih.gov/pubmed/26903989 http://dx.doi.org/10.3389/fmicb.2016.00110 |
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